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Tag: diabetic peripheral neuropathy

A Combined Treatment Protocol for Patients With Diabetic Peripheral Neuropathy

Wendy M. Ferx, MS, PT; Meredith R. Hall, DPT

FEDERAL PRACTITIONER, September 2015, 68-73


Study Summary

All of the 33 patients who qualified for this study (conducted at a Veterans Administration Hospital) were diagnosed with diabetes, foot pain, discomforting foot sensations and impaired balance. All patients first received 12 clinic-based treatments that included Anodyne and manual physical therapy.  Following completion of the clinic-based protocol, the study evaluated the real-life results of ongoing unsupervised home use of Anodyne therapy. Physical therapists evaluated changes in neuropathic symptoms in response to 3 and 6 months of home use of Anodyne therapy by these patients.



Patients who received 12 clinic-based Anodyne treatments in the manner described in the study, experienced substantial foot pain relief, reduction in fall risk, reversed the loss of protective sensation and improved their functional ability.

After both 3 and 6 months of unsupervised Anodyne home use, these patients obtained continued:

  • Pain Relief
  • Improved Mobility and Balance
  • Improved Activities of Daily Living
  • Reduced Fall Risk
  • Increased Foot Sensation
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Reversal of Diabetic Peripheral Neuropathy with MIRE

Reversal of diabetic peripheral neuropathy with phototherapy (MIRE™) decreases falls and the fear of falling and improves activities of daily living in seniors

Mark W. Powell, Dale H. Carnegie, Thomas J. Burke
Age and Ageing 2006; 35: 11–16


Study Summary

The 252 patients who qualified for this study suffered from type 2 Diabetes. They all self-treated with the Anodyne at home after first receiving Anodyne and physical therapy in a clinical setting. Study patients responded to a written health questionnaire designed to determine benefits of ongoing home treatment with Anodyne after approximately 9 months.




87% of patients continued to report foot pain relief, including:

  • 72% increased their activities of daily living
  • 79% diminished fear of falling
  • 76% reported fewer falls after treatment than before
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Restoration of Sensation, Reduced Pain, and Improved Balance in Subjects With Diabetic Peripheral Neuropathy

A double-blind, randomized, placebo-controlled study with monochromatic near-infrared treatment

David R. Leonard, MD, FACE, Hamed Farooqi, MD, FACE, Sara Myers, RN
Diabetes Care 27:168–172, 2004


Study Summary

All 27 patients who qualified for this study were diagnosed with Type 2 diabetes, foot pain/discomforting foot sensations and impaired balance.

Patients received either 6 or 12 Anodyne treatments rendered in a diabetes center.



Patients who received Anodyne, in the manner described in the study, obtained significant pain relief after 2 weeks and 4 weeks of treatment but not sham treatment, including:

  • Relief from discomforting foot sensations improved more in response to active treatment than to sham treatment.
  • Balance improved in 50% of patients
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Improvement of Sensory Impairment in Patients with Peripheral Neuropathy

Joseph Prendergast, MD, Galdina Miranda, MA, Manuel Sanchez, MA 
24 ENDOCRINE PRACTICE Vol 10 No. 1 January/February 2004


Study Summary

The 27 patients who qualified for this study exhibited pain/discomforting foot sensations and abnormal sensory values using a Neurometer device.  21 patients were diagnosed with diabetes and 6 were diagnosed with other conditions that may have been associated with their symptoms.

Patients received 10 Anodyne treatments over 2 weeks in the medical office of an endocrinologist.



96% of patients receiving Anodyne treatments obtained significant relief from their pain/discomforting foot sensations, including:

  • 61% reduction of impairment
  • 60% were tested as having normal sensory function after treatment compared to 0% prior to treatment
  • All patients who had previously failed to respond to conservative prescription medications for their symptoms (average of 7 years) improved after receiving treatment
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Monochromatic Infrared Photo Energy in Diabetic Peripheral Neuropathy

Tarek A. Ammar, PT, PhD
ISRN Rehabilitation, Volume 2012, Article ID 484307, 8 pages


Study Summary

All of the 35 patients who qualified for this study were diagnosed with diabetes, foot pain/discomforting foot sensations and impaired balance.  Half of patients received 12 treatments that included Anodyne, manual physical therapy and home exercise. The remainder received the same 12 treatments but without Anodyne.



Anodyne treated patients obtained better results than those who just received physical therapy and home exercises alone, including:

  • 33% more pain relief
  • 6 times the reduction in discomforting foot sensations
  • 2.5 times the improvement in balance
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