- Anodyne Therapy - https://www.anodynetherapy.com -

Clinical Evidence

About Our Research

The First Cleared by the FDA

In 1994, the FDA cleared the Anodyne Therapy System for human use. This was the first product using infrared LEDs cleared to increase circulation and relieve pain. Over 20 years later, Anodyne continues its market leadership in evidence-based light therapy products.

Anodyne is Proven

25 studies published since 1999 in noted medical journals show the pain relieving benefits of the Anodyne Therapy Systems in nearly 5,000 patients. Anodyne studies are published in medical journals such as Diabetes Care, Practical Pain Management, Age and Ageing, and Endocrine Practice. Most of the studies about Anodyne and pain relief relate to foot and leg pain, knee pain and lower back pain.

Don't Be Fooled

All light therapy products are not alike even if they have all been cleared by the FDA. Unlike Anodyne, most light therapy products have no published evidence that they work. They rely solely on testimonials, general scientific evidence related to light therapy in general or studies conducted with other peoples’ products.

Anodyne Therapy is MIRE

Throughout our studies, the acronym MIRE is referenced. MIRE is Monochromatic Infrared Energy and is a trademark of Anodyne Therapy technology specifically.

Published Clinical Data

Foot Pain Studies

This is the most studied topic for the use of Anodyne, which includes 15 published studies that detail the benefits obtained by more than 4,000 patients. Looking at these studies collectively, the vast majority of patients responded to treatments that included Anodyne and that the average pain relief was more than 50%. Publications include:

  • Alan B. Kochman, MSPT, Dale H. Carnegie, DPM, Thomas J. Burke, PhD. J Am Podiatr Med Assoc 2002
  • Joseph Prendergast, MD, Galdina Miranda, MA, Manuel Sanchez, MA.  24 ENDOCRINE PRACTICE Vol 10 No. 1 January/February 2004
  • Alan B. Kochman, MSPT J. Geriatr Phys Ther. 2004
  • David R. Leonard, MD, FACE, Hamed Farooqi, MD, FACE, Sara Myers, RN
    Diabetes Care 27, 2004
  • Salvatore L. DeLellis, DPM, Dale H. Carnegie, DPM, Thomas J. Burke, PhD. J Am Podiatr Med Assoc 2005
  • Lawrence B. Harkless, DPM, Salvatore DeLellis, DPM, Dale H. Carnegie, DPM, Thomas J. Burke, PhD. Journal of Diabetes and Its Complications. 2006
  • Wendy Volkert, MSPT, Ahmed Hassan, PT, MS, Mohamed A. Hassan, PT, MHS, Vicki L. Smock, PT, Justin P. Connor, PT, Becky McFee, PT, Shayne K. Ferguson, PT, MHS, PhD, GCS, CWS, Thomas J. Burke, PhD. Physical & Occupational Therapy in Geriatrics, Vol. 24(2) 2006
  • Mark W. Powell, Dale H. Carnegie, Thomas J. Burke. Age and Ageing 2006
  • Thomas J. Burke, PhD. Practical PAIN MANAGEMENT, July/August 2007
  • Palanghi F., DeBellis A., Gioffredi M., Gori R., Picciafouchi R., Martini N., Anichini R. European Association for the Study of Diabetes 2009
  • Stanley Paul, Yuanlong Liu, Robert McAlister. Indian Journal of Physiotherapy and Occupational Therapy. January-March 2010
  • Tarek A. Ammar, PT, PhD. International Scholarly Research Network Rehabilitation ISRN Rehabilitation, 2012
  • Wendy M. Ferx, MS, PT; Meredith R. Hall, DPT. FEDERAL PRACTITIONER, September 2015

Knee & Back Pain Studies

The authors of the following published studies describe pain relief obtained with the Anodyne Therapy System compared to conventional treatments. Looking at these studies collectively, the vast majority of patients responded to treatments that included Anodyne and that the average pain relief was more than 50%.

  • Tarek A. Anmar, PT, PhD. Bull. Fac. Ph.Th.Cairo Univ., Vol. 15, No. (2) Jul. 2010 (Knee pain relief)
  • Tarek Anmar, PT, PhD. Lasers Med Sci 2014; 5(4):176-82 (Knee Pain Relief)
  • Ru-Lan Hsieh & Wen-Chung Lee. Lasers Med Sci DOI 10.1007/s10103-013-1378-2 (Back pain relief)
  • Tarek Abdel, Rahman Ali Anmar. Journal of Lasers in Medical Science, 2015, 6(4): 157-161
To request published Anodyne studies, click here [3]

Increases in Circulation

Blood Flow Laser Doppler Imaging

Circulation increases were measured by a Moor Scanning Laser Doppler after a 20 - 30 minute Anodyne Therapy treatment. Brighter areas in the images below indicate increased circulation.

UP TO 3200% INCREASE
UP TO 2000% INCREASE
UP TO 1300% INCREASE
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