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About Our Research

The First Cleared by the FDA

The Anodyne Therapy System was the first product that used light for pain relief that the FDA believed worthy to clear for human use in 1994. Anodyne continues its market leadership in evidence-based light therapy products.

Anodyne is Proven

25 studies published in noted medical journals prove the pain relieving benefits of the Anodyne Therapy Systems. These studies used Anodyne products not some other device. Anodyne studies are published in such recognized medical journals as Diabetes Care, Practical Pain Management, Age and Ageing, and Endocrine Practice.

Don't Be Fooled

All light therapy products are not alike even if they have all been cleared by the FDA. Unlike Anodyne, most light therapy products have no published evidence that they work. They rely solely on testimonials, general scientific evidence related to light therapy in general or studies conducted with other peoples’ products.

Anodyne Therapy is MIRE

Throughout our studies, the acronym MIRE is referenced. MIRE is Monochromatic Infrared Energy and is a trademark of Anodyne Therapy technology specifically.

Published Clinical Data

Foot Pain Studies

The authors of the following published studies describe pain relief obtained
by over 4,000 patients who received treatment with the Anodyne Therapy System.

Monochromatic Infrared Photo Energy in Diabetic Peripheral Neuropathy


Patients treated with Anodyne Therapy obtained more pain relief than those who were not treated with Anodyne.

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Infrared Photo Energy May Reduce Neuropathic Pain


Patients who received Anodyne Therapy treatments experienced a 64% reduction in pain.

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Effectiveness of Monochromatic Infrared Photo Energy and PT for Peripheral Neuropathy


More than 90% of patients obtained significant foot pain relief.

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Symptomatic Reversal of Peripheral Neuropathy in Patients with Diabetes


94% of patients reported significant relief from their pain/discomforting foot sensations.

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Improvement of Sensory Impairment in Patients with Peripheral Neuropathy


96% of patients obtained relief from pain/discomforting foot sensations.

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Restoration of Sensation, Reduced Pain, and Improved Balance in Subjects With Diabetic Peripheral Neuropathy


Patients obtained significant pain relief after both 2 and 4 weeks of treatment.

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Reversal of Diabetic Peripheral Neuropathy with MIRE


87% of patients reported continuing foot pain relief after 9 months!

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A Combined Treatment Protocol for Patients With Diabetic Peripheral Neuropathy


Following completion of the clinic-based protocol, the study evaluated the real-life results of ongoing unsupervised home use of Anodyne Therapy.

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The Efficacy of Monochromatic Infrared Photo-Thermal Energy Therapy in Rehabilitation: A Pilot Study report


Patients receiving treatments with Anodyne Therapy showed significant pain relief, improved feeling, and better balance.

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Near-Infrared Photo Energy Therapy (Anodyne) could Reduce Diabetic Peripheral Neuropathic Pain


More than 88% of patients receiving treatments with Anodyne Therapy and physical therapy obtained significant pain relief and used less pain relieving pain medications.

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Knee & Back Pain Studies

The authors of the following published studies describe pain relief obtained with the Anodyne Therapy System compared to conventional treatments.

About Our Clinical Evidence

These summaries are intended to fairly summarize the results in published studies. However, we suggest a review of the entire published studies to reach an independent understanding of the reported results and study limitations.

Individual response may differ from those reported in these published studies.

Anodyne is Anodyne Therapy, which is cleared by the FDA for the relief of pain, increase in circulation and reduction of muscle spasm. Our company, Anodyne Therapy, LLC only states that there is change in painful and discomforting symptoms in response to treatment; it does not make any additional marketing claims nor does it make any claim that Anodyne Therapy treats or cures the underlying diagnosis potentially causative of painful symptoms.

Increases in Circulation

Blood Flow Laser Doppler Imaging

Circulation increases were measured by a Moor Scanning Laser Doppler after a 20 - 30 minute Anodyne Therapy treatment. Brighter areas in the images below indicate increased circulation.

UP TO 3200% INCREASE
UP TO 2000% INCREASE
UP TO 1300% INCREASE
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